ABSTRACT
Aim: We assessed safety of high-intensity [IV1] constant-load exercise (CLE) and intermittent exercise (HIIT) in 14 post-severe-COVID-19 patients (63+/-13 years;78.6% male;BMI: 28+/-5, without comorbidities) between July 2020 and April 2021 after 55+/-22 days of COVID-induced acute respiratory failure. Method(s): The crossover study balanced exercise intensity between CLE at 70% of peak work rate (WRpeak) to the limit of tolerance (Tlim) and HIIT including 1 min exercise at 100% WRpeak, alternated with 1 min at 40% WRpeak to Tlim. Gas exchange, ventilation, electrocardiography and symptoms were assessed. Result(s): Exercise endurance time and total work output were not different between HITT and CLE (Table 1). At Tlim, none of the ventilatory or cardiovascular responses differed between HITT and CLE and there was no difference in the intensity of symptoms (Table 1). Conclusion(s): Individuals with ongoing symptomatic COVID-19 could safely undertake high intensity exercise performed continuously or intermittently.